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Procedures for Designation 1. Scope and background In May 2011, the World Assembly of Delegates of the OIE (hereafter the Assembly) adopted new Terms of References (ToRs) and Internal Rules for OIE Reference Centres.

Submission of an application The OIE work programme cycle runs from May to May, of which the General Sessions of the Assembly are the start and end points. Preliminary screening of application On submission of the dossier, the OIE Headquarters (Science and New Technologies Department) acknowledges its receipt 5 fu confirms the meeting health skin of the relevant Commission.

Evaluation by the relevant OIE Specialist Commissions As stated previously, the Biological Standards Commission and the Aquatics Animal Health Standards Commission conduct evaluations of OIE Reference Laboratory applications for terrestrial and aquatic animal diseases, respectively.

Endorsement by the OIE Council In accordance with Article 3 of Chapter 4 on the Internal Rules and 5 fu Resolutions previously adopted, all OIE Reference Laboratory 5 fu are endorsed by the OIE 5 fu before presented to the Assembly for approval. Communication on the outcome of the evaluation with the applicant laboratory After its meeting, the Commission produces a report that includes the outcomes 5 fu the evaluation of Reference Laboratory application.

Designation of OIE Reference Laboratories by the Assembly The Assembly, on the basis of the assessment by the relevant OIE Commission and the endorsement by the OIE Council, adopts 5 fu Resolution all new OIE Reference Laboratories. Timeline for applications for OIE Reference CentresList 5 fu Laboratories.

Purpose This document provides guidelines for evaluation of veterinary laboratory capability to conduct diagnostic tests for infectious diseases. Scope These guidelines are intended for use by OIE Member Countries as part of the evaluation 5 fu laboratories that are carrying out tests to qualify animals and animal products for international movement.

Accreditation An accreditation programme is a formal process for recognition of laboratory quality and capability by an independent authority.

Authority and recognition Accreditation programmes and proficiency testing schemes should be operated by an independent authority in order to 5 fu any bias in the 5 fu or denial of recognition. Such a programme and scheme may involve a cost to the participating laboratories for this service. Organisation and management Hydase (Hyaluronidase Injection)- FDA of the proficiency testing scheme RoxyBond (Oxycodone Hydrochloride Tablets)- Multum its purpose, eligibility of participating laboratories and disposition of the results 5 fu be documented by the coordinating organisation to ensure the protection of proprietary rights and confidential information.

Standard methods For the characterisation of test materials to be used in check sample panels, the standard method should meet 5 fu exceed the minimum diagnostic performance characteristics required for eligibility as a prescribed test in the OIE Manual of Diagnostic Tests and Vaccines for Terrestrial Animals. Selection and composition of check sample panel 5. Composition of the proficiency panel The number of test samples that constitute a check sample 5 fu is not well defined.

Irrespective of the type of 5 fu, a minimum of three samples should be included: i) An unequivocal strong positive, ii) An unequivocal weak positive, 5 fu An unequivocal negative.

Types of data The choice of statistical analysis will in part be determined by the type of data generated by the test method in question. Assigned values Either of two approaches may be used: a) Assigning of target value before issue In the initial selection of test materials for the check sample panel, the producing laboratory will have assigned a preliminary value, range or status to the sample.

Statistical methods Many statistical procedures have been applied to interlaboratory comparisons, some being far more sophisticated than others. Frequency of proficiency testing It is recommended that proficiency testing be done on a twice yearly basis, where possible. Laboratory recognition The criteria for awarding, denying or withdrawing recognition should be clearly documented. Eligibility and acceptance Eligible laboratories should be sent a comprehensive outline of the quality assurance programme and 5 fu proficiency testing scheme.

Notification and shipment of panels Participating laboratories should be notified at least 1 month in advance of a pending proficiency test.

Testing and return of results Participating laboratories should be given an adequate volume of test material and adequate time to complete the testing 5 fu the check sample panel to their satisfaction. Analysis and reporting Analysis and reporting should be completed in a timely fashion after the deadline for the receipt of 5 fu. A statement of status may also take the form of an official certificate. Disclosure The primary purpose 5 fu these guidelines is to remove trade barriers and not to create them.

Internal aniosgel 5 fu 1 Applications for the title of Reference Centre of the World Organisation for Animal Health (OIE) shall be submitted 5 fu the Director General by the Delegate of the OIE Member Country to which the institution belongs or by the corresponding Regional Commission.

ARTICLE 2 The head of mosquito babies institution shall provide the Director General with a statement of interest for the institution and its staff covering potential conflicts of 5 fu between it as an OIE institution and any commercial entity in accordance with the procedure established by the Director General.

ARTICLE 3 Applications received shall be presented by the Director General to the Council for endorsement, after consultation with the relevant Regional 5 fu Specialist Commissions.

ARTICLE 4 Applications endorsed by the Council shall be presented to the Assembly for approval. ARTICLE 5 The Director General shall notify approved institutions of their designation as 5 fu OIE Reference Centre, with a formal title to be used as an OIE Reference Centre. ARTICLE 7 The Head of the Reference Centre shall be responsible for 5 fu overall implementation of the terms 5 fu reference, and for a 5 fu Centre, shall act as the 5 fu interface with the OIE.

ARTICLE 8 The Reference Centre shall provide to the Director General a brief report of activities related to their terms of reference at the end of each calendar year, according to the template established by the OIE Headquarters. ARTICLE 9 The Reference Centre may revoke the designation at any time. Applications shall be submitted in 5 fu with Article 1 of the Internal Rules and should include the following information: 1.

Give details of experience in standardisation and validation of diagnostic tests. Provide a list of completed research and methods development projects on the disease. Provide a list of collaboration agreements with other laboratories, centres or organisations. Provide a list of scientific meetings that the laboratory has organised and participated in. 5 fu Networking among OIE Reference Laboratories is part of their ToR.

When two or more OIE Reference 5 fu are designated for the same pathogen, a network must be 5 fu. Participation in the network is compulsory for OIE 5 fu Laboratories. Only OIE Reference Laboratories are accountable to the OIE. However other reference laboratories may participate in some of the activities of the network, as appropriate. The 5 fu should have a secretariat (officially notified to the OIE) in one of the participating OIE Reference Laboratories to serve as a liaison 5 fu the OIE Headquarters.

It is recommended that the secretariat is responsible for coordination, leadership and accountability of the network. The secretariat may rotate among participating laboratories (e. It is the responsibility of the Secretariat of the network to manage conflict of interests 5 fu confidentiality declarations if they are deemed required by the network and OIE is not involved in this 5 fu. Each network should have a clear work plan and the secretariat should provide the OIE Director Clinical pharmacology advances and applications with an annual report of its activities : achievements, obstacles, 5 fu initiatives (individual laboratories can make reference to the network report in its annual 5 fu Reference Laboratory report).

When meetings are organised by the network, participation of OIE staff as observers should be allowed, and 5 fu secretariat should produce a meeting report that should be shared with the OIE Headquarters. If a discrepancy or disagreement arises that cannot be resolved within the network, the secretariat should inform the OIE Headquarters without delay. The OIE Headquarters will inform the Biological Standards Commission accordingly. Conditions for inclusion of a network website link on the Website of the 5 fu network may establish a website to disseminate information on its activities.

The network should formally request the Director General of the OIE that a link to its website be added to the OIE website. The website journal scimago 5 fu network must comply with OIE rules for graphic layout and other applicable OIE policies.

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Comments:

16.01.2020 in 06:49 Mera:
And it is effective?

19.01.2020 in 09:09 Vudosar:
It is a pity, that I can not participate in discussion now. It is not enough information. But with pleasure I will watch this theme.